As with most risks, sure, you can try predicting the odds of positive results. But there is absolutely no certainty of anything.
A negative consequence perhaps Clinton didn't take seriously was that her protected daughter Chelsea would become fair game, finally.
Enemies, seasoned journalists and the concerned have pushed back on "Hard Choices" with their own books. Among the most influential is Daniel Halper's "Clinton, Inc."
In it he takes on Chelsea. That has opened the door wide for other members of the media, politicos and private citizens also to scrutinize the Former First Daughter. They are applying the same brutal methods of inspection which they inflicted and still inflict on Mama Bear and Papa Bear.
Now, Baby Bear could be mauled. The start of that is the tough analysis by Maureen Callahan in the New York Post. Yes, the NYP, owned by News Corp, is a conservative newspaper. However, in the competitive arena of media, all journalists will be pulling out all stops searching for an angle on Baby Bear. Here is the NYP's.
I suspect one or more deconstructions of Baby Bear will posit a Tragic Flaw. From then on, there will be a Greek Chorus chanting about it, every time the former First Daughter appears in public. Becoming a mother won't insulate her. She had her insulation.